This pilot study provides preliminary support for in-home dynamic light therapy to address sleep-related symptoms in acquired brain injury. Changes in other outcomes were non-significant. Treatment comprised daytime blue-enriched white light (CCT > 5000 K) and blue-depleted light ( 0.80). Following 2-week baseline, participants completed each condition for 2 months in counter-balanced order, with 1-month follow-up. Participants ( N = 24, M ± SD age = 44.3 ± 11.4) had mild-severe TBI or stroke > 3 months previously, and self-reported fatigue (Fatigue Severity Scale ≥ 4). Outcomes were fatigue (primary outcome), daytime sleepiness, sleep disturbance, insomnia symptoms, psychomotor vigilance, mood and activity levels. The impact of exposure to a dynamic light intervention (Treatment) was compared to usual lighting (Control) in a randomized within-subject, crossover trial. Building on demonstrated efficacy of blue light delivered via a lightbox in reducing fatigue and daytime sleepiness after TBI, this study evaluated the efficacy of a novel in-home light intervention in alleviating fatigue, sleep disturbance, daytime sleepiness and depressive symptoms, and in improving psychomotor vigilance and participation in daily productive activity, following injury Methods Fatigue and sleep disturbance are debilitating problems following brain injury and there are no established treatments.
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